University of Toledo (UT) lab discovered a new methodology for the treatment of Alzheimer’s disease. The research is based on a chemical, which is currently a Food and Drug Administration (FDA) approved food additive, with the potent to treat the Alzheimer’s disease. The chemical found by the UT lab is – mini-GAGR, which is a chain of sugar. Such a chemical is extensively found in the edibles such as jams, pudding, and cake icing.
Increasing Alzheimer’s disease in the U.S. at an alarming rate is hard pressing the health organization to formulate an effective cure, in order to treat this disorder. The progressive disease leads to memory loss and mental issues. Furthermore, the person affected with the Alzheimer’s disease finds it difficult in learning and solving problems.
Over 5.7 Mn people in the U.S. suffer from the Alzheimer’s disease and it keeps on progressing with the rising number of geriatric population. The Alzheimer’s disease is the sixth leading disorder causing death of the individuals in the U.S. surpassing breast cancer and prostate cancer combined. In the year 2018, U.S. spent about US$ 277 Bn for the Alzheimer’s disease.
Alzheimer’s disease: The Brain Condition
The brain of the individual suffering from Alzheimer’s disease ages abnormally, owing to the piles of toxic materials and microscopic level changes occurring in the brain, way before the actual memory loss begins to happen. Abnormal protein particles with plagues keep on multiplying in the brain, which is utilized to diagnose the disorder.
These abnormal particles gradually intervene in the way the brain communicates as well as influence the sustainability of the brain cells. In normal conditions, the brain cells known as neurons, communicate effectively with the organs and muscles in the body. The existing treatment for the Alzheimer’s disease is only capable to target the symptoms and not its progression over time. The treatment that eliminates the plague is short lived and the individual is prone to regain the Alzheimer’s disease.
How does mini-GAGR Enhance Memory and Protect the Neurons from Dying?
Chemical, discovered by UT Lab that mini-GAGR results in the increase of Nrf2, a protein, which plays a pivotal role in regulating antioxidant system in a human body. Owing to this property of Nrf2, the protein reduces the level of harmful free oxygen radicals. This, in turn, slows down the toxic effects against neurons in this condition.
However, merely consuming food containing mini-GAGR would not be the ultimate treatment of Alzheimer, the lab is putting its efforts to develop a nasal spray with the contents of mini-GAGR for maximizing the chances of the protein in reaching the brain.